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Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

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Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
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Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

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Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
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Mechanism of Ciliary Motion01:05

Mechanism of Ciliary Motion

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The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities.
The cilia are made up of microtubules in a 9+2 arrangement, with nine microtubule doublet ring bundles, surrounding a pair of central singlet microtubule bundles. The doublet microtubule bundles are...
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Speciation Rates01:07

Speciation Rates

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Overview
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Morphogenesis02:19

Morphogenesis

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Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
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Video Experimental Relacionado

Updated: Aug 24, 2025

In situ Protocol for Butterfly Pupal Wings Using Riboprobes
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Cómo las alas de las mariposas obtuvieron su patrón

Marianne Espeland1, Lars Podsiadlowski1

  • 1Leibniz Institute for the Analysis of Biodiversity Change, Museum Koenig, Bonn, Germany.

Science (New York, N.Y.)
|October 20, 2022
PubMed
Resumen

Los elementos reguladores genéticos son la clave para la formación del patrón del ala de la mariposa. Comprender estos elementos ayuda a explicar la diversidad de diseños de alas en los lepidópteros.

Área de la Ciencia:

  • Biología del desarrollo
  • La genética
  • Biología evolutiva

Sus antecedentes:

  • Los patrones de las alas de las mariposas son complejos y diversos.
  • Los elementos reguladores de genes controlan la expresión génica y son esenciales para el desarrollo.

Objetivo del estudio:

  • Investigar el papel de los elementos reguladores de genes en la formación del patrón del ala de la mariposa.
  • Comprender cómo las variaciones genéticas de estos elementos contribuyen a la diversidad fenotípica.

Principales métodos:

  • Análisis genómico comparativo de los genes del patrón del ala.
  • Ensayos funcionales para comprobar la actividad del elemento regulador.
  • Enfoques bioinformáticos para identificar elementos conservados y divergentes.

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Principales resultados:

  • Se identificaron elementos reguladores genéticos específicos como cruciales para establecer patrones de alas distintos.
  • Las variaciones en estos elementos se correlacionan con las diferencias de color y forma.
  • El análisis evolutivo reveló una rápida divergencia de los elementos regulatorios que impulsan la evolución del patrón.

Conclusiones:

  • Los elementos reguladores genéticos son los principales impulsores de la evolución del patrón del ala de la mariposa.
  • La comprensión de estos elementos proporciona información sobre la base genética de la diversidad fenotípica.
  • Esta investigación pone de relieve la importancia del ADN no codificante en la formación de rasgos complejos.