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Variación genómica de una sola célula inducida por procesos mutacionales en el cáncer

Tyler Funnell1,2, Ciara H O'Flanagan3, Marc J Williams4

  • 1Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY, USA.

Nature
|October 26, 2022
PubMed
Resumen

Las alteraciones del número de copias de célula a célula impulsan la evolución del cáncer al crear variación genómica y fenotípica. Este estudio revela tres patrones de variación estructural distintos que influyen en la diversidad de las células cancerosas y los resultados en los cánceres de mama y de ovario.

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