Video Experimental Relacionado

Updated: Aug 16, 2025

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

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Interruptor de conformación dependiente del sustrato del clúster no cubano [4Fe-4S] en la heterodisulfuro reductasa

Vladimir Pelmenschikov1, Delfim Ferreira2, Sofia S Venceslau2

  • 1Institut für Chemie, Technische Universität Berlin, 10623 Berlin, Germany.

Journal of the American Chemical Society
|December 21, 2022
PubMed
Resumen

La heterodisulfuro reductasa (HdrB) contiene un grupo único de no cubanos [4Fe-4S]. La unión al sustrato causa un cambio conformacional de un estado cerrado a un estado abierto, que implica un interruptor de ligando de cisteína.

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