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Updated: Aug 2, 2025

Oligopeptide Competition Assay for Phosphorylation Site Determination
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Oligopeptide Competition Assay for Phosphorylation Site Determination

Published on: May 18, 2017

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Inducción de la biogénesis lisosómica y mitocondrial por fosforilación AMPK de FNIP1

Nazma Malik1, Bibiana I Ferreira1, Pablo E Hollstein1

  • 1Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.

Science (New York, N.Y.)
|April 20, 2023
PubMed
Resumen

El daño mitocondrial activa la proteína quinasa activada por monofosfato de adenosina (AMPK), que fosforila la proteína 1 que interactúa con la folliculina (FNIP1). Esto desencadena la translocación nuclear de TFEB, iniciando la biogénesis lisosomal y mitocondrial.

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