Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Genomics02:02

Genomics

36.5K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.5K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

13.6K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
13.6K
Next-generation Sequencing03:00

Next-generation Sequencing

91.5K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
91.5K
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

14.0K
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
14.0K
RACE - Rapid Amplification of cDNA Ends02:35

RACE - Rapid Amplification of cDNA Ends

6.4K
Rapid Amplification of cDNA Ends, or RACE, is one of the most effective methods to obtain a full-length cDNA from an mRNA sequence between a known internal region to the unknown sequence at the 5’ or 3’ end. The unknown region is cloned in the cDNA by a gene-specific primer that binds the known end, and a hybrid primer that attaches a predefined anchor sequence to the unknown end of the cDNA. The sequence in between is amplified by PCR with an anchor primer and a gene-specific...
6.4K
Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

44.0K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
44.0K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Who Speaks for the Dead? Of Communities and Stewardship in Legacy Collections of Human Remains.

American journal of biological anthropology·2026
Same author

AABA Task Force on the Ethical Study of Human Remains Recommendations: Proposal for the Management and Oversight of Community Partnership and Ethical Stewardship of Human Remains.

American journal of biological anthropology·2026
Same author

Persistent human-associated microbial signatures in burial soils from the 17th and 18th century New York African burial ground.

ISME communications·2025
Same author

Evolutionary perspectives on African North American genetic diversity: Origins and prospects for future investigations.

Evolutionary anthropology·2021
Same author

So many Nigerians: why is Nigeria overrepresented as the ancestral genetic homeland of Legacy African North Americans?

American journal of human genetics·2020
Same author

Historical overview, current research, and emerging bioethical guidelines in researching the New York African burial ground.

American journal of physical anthropology·2020

Video Experimental Relacionado

Updated: Jul 20, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.2K

La genómica por iniciativa de la Comunidad

Fatimah L C Jackson1

  • 1Howard University and QuadGrid Data Lab, Washington, DC, USA.

Science (New York, N.Y.)
|August 3, 2023
PubMed
Resumen
Este resumen es generado por máquina.

El análisis de ADN antiguo ayuda a vincular a los afroamericanos esclavos históricos con sus descendientes vivos. Esta investigación genética proporciona conexiones cruciales para el entendimiento genealógico e histórico.

Más Videos Relacionados

CIRCLE-Seq for Interrogation of Off-Target Gene Editing
08:23

CIRCLE-Seq for Interrogation of Off-Target Gene Editing

Published on: November 1, 2024

684
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.2K

Videos de Experimentos Relacionados

Last Updated: Jul 20, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.2K
CIRCLE-Seq for Interrogation of Off-Target Gene Editing
08:23

CIRCLE-Seq for Interrogation of Off-Target Gene Editing

Published on: November 1, 2024

684
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.2K

Área de la Ciencia:

  • La genética
  • Antropología
  • Su historia

Sus antecedentes:

  • La investigación genealógica para los afroamericanos a menudo se ve obstaculizada por los registros históricos.
  • El ADN antiguo (ADN) ofrece una vía potencial para cerrar lagunas en el registro histórico.

Objetivo del estudio:

  • Investigar la utilidad del ADN antiguo para establecer vínculos genéticos entre individuos históricos y poblaciones contemporáneas.
  • Para explorar la aplicación del ADN en la genealogía afroamericana.

Principales métodos:

  • Extracción y secuenciación de ADN de los restos esqueléticos.
  • Análisis genómico comparativo con bases de datos de ADN modernas.
  • Aplicación de los principios de la genética de poblaciones.

Principales resultados:

  • Identificación exitosa de marcadores genéticos que conectan las muestras antiguas con los descendientes afroamericanos modernos.
  • Demostración de la viabilidad de un ADN en el rastreo de linaje a través de generaciones.

Conclusiones:

  • El análisis de ADN antiguo es una herramienta poderosa para reconectar a los descendientes con su pasado ancestral.
  • Esta metodología puede mejorar significativamente nuestra comprensión de la historia y la identidad afroamericana.