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Updated: Jul 15, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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Published on: February 6, 2019

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Síntesis total convergente de la (-) -ciclopamina

Manolis Sofiadis1, Dongmin Xu1, Anthony J Rodriguez1

  • 1Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|October 2, 2023
PubMed
Resumen

Este estudio presenta una síntesis total concisa y enantioselectiva de la ciclopamina alcaloide de Veratrum. Los pasos clave incluyen la formación de nuevos heterociclos y la construcción de motivos espirocíclicos para una síntesis eficiente.

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