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Updated: Jul 12, 2025

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
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Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

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Síntesis total enantioselectiva de (-) -artatrovirenol A

Rémi Lavernhe1, Patrick Domke1, Qian Wang1

  • 1Laboratory of Synthesis and Natural Products (LSPN), Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, EPFL-SB-ISIC-LSPN, BCH5304, CH-1015 Lausanne, Switzerland.

Journal of the American Chemical Society
|October 24, 2023
PubMed
Resumen

Este estudio detalla la primera síntesis total enantioselectiva de (-) -artatrovirenol A, un sesquiterpenoide único con forma de jaula. Los pasos clave incluyeron las reacciones de Diels-Alder y Mukaiyama-Michael, que permitieron la construcción de este complejo producto natural.

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