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Los neurocircuitos para la motivación

Garret D Stuber1,2,3

  • 1Center for the Neurobiology of Addiction, Pain, and Emotion, University of Washington, Seattle, WA 98195, USA.

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PubMed
Resumen
Este resumen es generado por máquina.

Los circuitos neuronales para los impulsos innatos regulan las neuronas de dopamina del área tegmental ventral (ATV), reforzando las acciones para los comportamientos motivados. Esto explica la dopamina

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Área de la Ciencia:

  • La neurociencia
  • Biología del comportamiento
  • Neurobiología

Sus antecedentes:

  • El sistema nervioso controla comportamientos motivados como alimentarse y escapar para sobrevivir.
  • Los comportamientos diversos comparten características comunes como el acercamiento / evitación, lo que sugiere sustratos neuronales compartidos.
  • Las neuronas de dopamina del área tegmental ventral (VTA) son cruciales para las acciones motivadas.

Objetivo del estudio:

  • Describir un marco para cómo los circuitos neuronales regulan las neuronas de dopamina del VTA.
  • Para explicar el papel ubicuo de la dopamina VTA en los comportamientos motivados.
  • Para aclarar cómo las señales inician acciones dirigidas a objetivos.

Principales métodos:

  • Este es un artículo de revisión, que sintetiza la investigación existente.
  • La revisión propone un marco teórico.
  • Integra los hallazgos sobre los circuitos neuronales y la señalización de la dopamina.

Principales resultados:

  • Los impulsos innatos utilizan circuitos neuronales para modular la actividad de las neuronas de dopamina del VTA.
  • Esta modulación refuerza las acciones en curso o planificadas para satisfacer las necesidades motivacionales.
  • El marco explica el papel de la dopamina en diversos comportamientos volitivos.

Conclusiones:

  • Los circuitos neuronales que controlan los impulsos innatos proporcionan un mecanismo para la regulación neuronal de la dopamina VTA.
  • Este mecanismo subyace a la participación de la dopamina en una amplia gama de comportamientos motivados.
  • Las señales sensoriales e interoceptivas se pueden integrar para iniciar acciones específicas dirigidas a través de este marco.