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Updated: Jul 12, 2025

Glycopeptide Capture for Cell Surface Proteomics
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Conformación restringida de la columna vertebral del glicopéptido inhibe la mezcla H/D en fase gaseosa entre las

Christian Code1,2, Danwen Qiu1, Ilia A Solov'yov2,3,4,5

  • 1Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.

Journal of the American Chemical Society
|October 26, 2023
PubMed
Resumen

La disociación inducida por colisión (CID) de los glicopéptidos puede revelar el contenido de deuterio de glicano. Sin embargo, la mezcla de hidrógeno / deuterio (H / D) durante la fragmentación impide un análisis preciso en la mayoría de las glicoproteínas, a diferencia de las moléculas conformacionalmente restringidas como la vancomicina.

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