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Electrosíntesis sin membrana de las epiclorhidrinas mediadas por radicales de bromo sobre nanotipos

Ying Gao¹, Mingming Yan¹, Chuanqi Cheng²

¹Department of Chemistry, School of Science, Institute of Molecular Plus, Tianjin University, Tianjin 300072, China.

Journal of the American Chemical Society

|December 29, 2023

Resumen

Este estudio presenta una nueva electrosíntesis de epiclorhidrina (ECH) en un solo recipiente utilizando radicales de bromo, evitando el cloro corrosivo y los procesos en varios pasos. El método alcanza una alta eficiencia y tasa, ofreciendo una ruta económicamente viable para la producción de ECH.

Área de la Ciencia:

La electroquímica
Síntesis orgánica
Ciencias de los materiales

Sus antecedentes:

La fabricación tradicional de epiclorhidrina (ECH) incluye cloro corrosivo y procesos complejos de varios pasos.
El desarrollo de rutas sintéticas sostenibles y eficientes para el ECH es crucial para la industria química.
La electrosíntesis ofrece una alternativa prometedora para una producción química más limpia.

Objetivo del estudio:

Desarrollar un método de electrosíntesis sin membrana para la epiclorhidrina (ECH).
Utilizar los radicales de bromo para una producción eficiente de ECH, minimizando los subproductos y mejorando la sostenibilidad.
Investigar el papel del electrocatalizador NiCo2O4 y el diseño de electrodos nanoestructurados en el rendimiento de la reacción.

Principales métodos:

Electrosíntesis de ECH mediante una vía mediada por el radical Br.
Desarrollo de un catalizador de NiCo2O4 con una nanoestructura específica (nanotipos de alta curvatura).
Investigación electroquímica de los mecanismos de reacción, incluida la oxidación *OH y la adsorción Br.
Análisis tecnoeconómico para evaluar la rentabilidad.

Principales resultados:

Se logró una eficiencia Faradaic del 47% para la producción de ECH.
Se obtuvo una alta velocidad de reacción de 1,4 mol h−1 gcat−1 a una densidad de corriente de 100 mA cm−2.
El catalizador NiCo2O4 suprimió efectivamente las reacciones de evolución competitivas de oxígeno y bromo.
Se ha demostrado la rentabilidad económica y la universalidad metodológica de la síntesis de epóxidos.

Conclusiones:

La electrosíntesis mediada por radicales Br desarrollada es un método eficiente y económicamente viable para producir ECH.
Las propiedades únicas del catalizador NiCo2O4 y la nanoestructura del electrodo son clave para el éxito del proceso.
Este enfoque muestra el potencial para la síntesis sostenible de ECH y los intermediarios de fármacos epóxidos relacionados.

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