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The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

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Patient-Reported Symptom Burden Among Thyroid Cancer Survivors: Retrospective Cohort Study.

JCO clinical cancer informatics·2026
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Prevalence of Germline Pathogenic <i>RET</i> Variants in a Pan-Cancer Patient Population.

JCO precision oncology·2026
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PRECISE: A Prognostic Thyrocyte-Derived Gene Signature for Papillary Thyroid Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
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A differentiated thyroid carcinoma-specific graded prognostic assessment for brain metastases: derivation in a 10,306-patient cohort and external validation.

Journal of neuro-oncology·2026
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Systemic Treatment of Thyroid Cancer: ASCO Guideline.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026
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Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications.

Head & neck·2026

Video Experimental Relacionado

Updated: Jul 4, 2025

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

539

Cáncer de tiroides: un repaso

Laura Boucai1, Mark Zafereo2, Maria E Cabanillas3

  • 1Department of Medicine, Division of Endocrinology, Memorial Sloan Kettering Cancer Center, New York, New York.

JAMA
|February 6, 2024
PubMed
Resumen
Este resumen es generado por máquina.

Esta revisión cubre el diagnóstico y el tratamiento del cáncer de tiroides, destacando que la mayoría de los cánceres de tiroides bien diferenciados son curables con cirugía y yodo radiactivo, mientras que los casos avanzados se benefician de terapias dirigidas.

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Área de la Ciencia:

  • En el campo de la oncología
  • Endocrinología

Sus antecedentes:

  • La incidencia de carcinoma de tiroides en los Estados Unidos es significativa, con un estimado de 43.720 nuevos casos en 2023.
  • La tasa general de supervivencia relativa a 5 años para el cáncer de tiroides es de aproximadamente el 98,5%.

Conclusiones:

  • La cirugía sigue siendo el tratamiento curativo primario para la mayoría de los cánceres de tiroides bien diferenciados.
  • La terapia con yodo radiactivo mejora la supervivencia de los pacientes de alto riesgo.
  • Las terapias emergentes como los inhibidores antiangiogénicos de la multikinasa y los tratamientos dirigidos a la mutación son cruciales para el manejo del cáncer de tiroides metastásico y refractario.