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Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
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Cuadros orgánicos covalentes con quiralidad sintonizable para la selectividad de espín inducida por quiral
Xing Han1, Chao Jiang1, Bang Hou1
1School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China.
Journal of the American Chemical Society
|February 28, 2024
Resumen
Los marcos orgánicos covalentes quirales (CCOF) demuestran una eficiente selectividad de espín inducida por quiralidad (CISS) para aplicaciones de filtro de espín. Esta investigación presenta CCOF-9-Co, un nuevo material que exhibe una polarización de espín significativa para dispositivos espintrónicos avanzados.
Área de la Ciencia:
- Ciencias de los materiales
- Química orgánica
- La tecnología Spintronics
Sus antecedentes:
- Los marcos orgánicos covalentes quirales (CCOF) son prometedores para aplicaciones enantioselectivas.
- La selectividad de espín inducida por quiralidad (CISS) ofrece una nueva ruta para la inyección de corriente polarizada sin capas magnéticas.
- La explotación del CISS dentro de los CCOF sigue siendo un área de investigación poco explorada.
Objetivo del estudio:
- Investigar los CCOF como una plataforma para el desarrollo de materiales de filtro de espín con CISS eficiente.
- Diseñar y sintetizar una nueva familia de CCOF 2D basados en Zn (salina).
- Para explorar el efecto CISS en un CCOF sustituido por cobalto.
Principales métodos:
- Síntesis de CCOFs-9-12 a través de la condensación de imina.
- Estudios de adsorción enantioselectiva con el uso de fármacos racémicos.
- Fabricación y caracterización del CCOF-9-Co.
- Microscopía de fuerza atómica conductiva magnética (MC-AFM) para medir el CISS.
- Espectroscopia de dicroísmo magnético circular (MCD).
Principales resultados:
- CCOF- 9 demostró una alta enantioselectividad (hasta el 97% ee) para la adsorción de fármacos racémicos.
- CCOF-9-Co exhibió una conductividad mejorada y retuvo la cristalinidad y la porosidad.
- El MC-AFM reveló un efecto CISS significativo en el CCOF-9-Co (relación de polarización de espín del 88-94%).
- MCD confirmó el fenómeno CISS bajo un campo magnético externo.
Conclusiones:
- Los CCOF son una plataforma viable para crear materiales de filtro de espín con un CISS eficiente.
- El CCOF-9-Co representa un nuevo material con un potencial sustancial para aplicaciones espintrónicas.
- Este estudio abre caminos para el diseño de nuevos polímeros cristalinos con fuertes efectos CISS.
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