Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Stereoisomerism02:52

Stereoisomerism

11.9K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
11.9K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

7.9K
Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
7.9K
Structural Isomerism02:34

Structural Isomerism

19.2K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can...
19.2K
Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

2.5K
Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.5K
Valence Bond Theory02:42

Valence Bond Theory

8.5K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
8.5K
Protein Complex Assembly02:41

Protein Complex Assembly

10.6K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
10.6K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

A Multi-Stimuli Transformational Network of Benzil-Based Pd(II) Assemblies.

Angewandte Chemie (International ed. in English)·2026
Same author

Overcrowded Alkene Photo-Redox-Switches Based on Quinolinium/Carbene Building Blocks.

Angewandte Chemie (International ed. in English)·2026
Same author

Programming Palladium Cage Geometry through Ligand Redox Modulation.

Angewandte Chemie (International ed. in English)·2026
Same author

Organophosphides: A New Class of Luminophore Ligands for Copper(I) Carbene Based TADF Emitters and Photocatalysts.

Angewandte Chemie (International ed. in English)·2026
Same author

Non-Statistical Assembly of Donor-Acceptor Cages for Light-Induced Charge Separation.

Angewandte Chemie (International ed. in English)·2026
Same author

Dual Cation/Anion Binding in Crown Ether-Based Coordination Cages.

Journal of the American Chemical Society·2025

Video Experimental Relacionado

Updated: Jul 1, 2025

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents
09:01

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents

Published on: July 8, 2015

12.6K

Autoclasificación Heteromérica y Completa en Sistemas de Jaulas de Coordinación

Elie Benchimol1, Irene Regeni1, Bo Zhang1

  • 1Department of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn Str. 6, Dortmund 44227, Germany.

Journal of the American Chemical Society
|February 29, 2024
PubMed
Resumen

Los investigadores demuestran

Más Videos Relacionados

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.3K
Comparing the Affinity of GTPase-binding Proteins using Competition Assays
10:37

Comparing the Affinity of GTPase-binding Proteins using Competition Assays

Published on: October 8, 2015

9.2K

Videos de Experimentos Relacionados

Last Updated: Jul 1, 2025

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents
09:01

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents

Published on: July 8, 2015

12.6K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.3K
Comparing the Affinity of GTPase-binding Proteins using Competition Assays
10:37

Comparing the Affinity of GTPase-binding Proteins using Competition Assays

Published on: October 8, 2015

9.2K

Área de la Ciencia:

  • Química de coordinación
  • Química supramolecular
  • Ciencias de los materiales

Sus antecedentes:

  • Las jaulas de coordinación heterolépticas se ensamblan a partir de múltiples tipos de ligando.
  • Los métodos existentes incluyen mezcla estadística o transformaciones de jaula a jaula.
  • El control de la formación de jaulas heterolépticas sigue siendo un desafío.

Objetivo del estudio:

  • Introducir y demostrar la "autoclasificación complementaria heteromérica" en los sistemas de jaulas de coordinación.
  • Para explorar la coexistencia controlada de jaulas heterolépticas distintas.
  • Investigar el papel de las relaciones de ligando y los factores entálpicos en los resultados de la autoclasificación.

Principales métodos:

  • Utilizando las transformaciones de jaula a jaula de los precursores homoleptos.
  • El uso de un enfoque de química de sistemas con diferentes proporciones de ligando.
  • Caracterización mediante resonancia magnética nuclear (RMN) y espectrometría de masas (SM).
  • Elucidación estructural mediante difracción de rayos X de un solo cristal.

Principales resultados:

  • Se ha demostrado la coexistencia de dos jaulas heterolépticas distintas (Pd2A2B2 y Pd2A2C2) mediante autoclasificación completiva heteromérica.
  • Se ha demostrado el control sobre el resultado de la autoclasificación mediante la variación de las proporciones de ligandos, pasando de la autoclasificación integrativa a la completa.
  • Las estructuras cristalinas obtenidas revelan diversos arreglos de ligandos (transfiguración de ocho, bordes cis, borde único) dictados por la composición de la jaula.

Conclusiones:

  • La autoclasificación completiva heteromérica ofrece un nuevo nivel de control sobre las poblaciones de jaulas heterolépticas.
  • Los factores entálpicos son determinantes cruciales pero controlables de la autoclasificación.
  • Este trabajo permite futuras aplicaciones en el procesamiento de la información, la selectividad adaptativa y la catálisis de respuesta.