Video Experimental Relacionado

Updated: Jun 30, 2025

Demonstration of Heterologous Complexes formed by Golgi-Resident Type III Membrane Proteins using Split Luciferase Complementation Assay
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Demonstration of Heterologous Complexes formed by Golgi-Resident Type III Membrane Proteins using Split Luciferase Complementation Assay

Published on: September 10, 2020

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Mecanismo de transporte y farmacología del GlyT1 humano

Yiqing Wei1, Renjie Li1, Yufei Meng1

  • 1Key Laboratory of Biomacromolecules (CAS), National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.

Cell
|March 21, 2024
PubMed
Resumen

Los conocimientos estructurales sobre el transportador de glicina 1 (GlyT1) revelan cómo reabsorbe la glicina y cómo se unen los medicamentos contra la esquizofrenia. Esto proporciona una base para el desarrollo de nuevos tratamientos dirigidos a los NMDAR para la esquizofrenia.

Palabras clave:
Se ha comprobado que elGlyT1 y GlyT2Se incluyen las siguientes categorías:Se incluyen las siguientes categorías:medicamentos para la esquizofreniaDeterioro cognitivoTransición conformacionalreabsorción de la glicinaReconocimiento del sustrato

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