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Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
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La vacuna contra la malaria de primera generación se ha aplicado con éxito en tres países africanos

Claudia A Daubenberger1, Joana C Silva2

  • 1Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland; University of Basel, Basel, Switzerland.

Lancet (London, England)
|April 7, 2024
PubMed
Resumen

No abstract available in PubMed .

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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
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