Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Aromatic Hydrocarbon Cations: Structural Overview01:18

Aromatic Hydrocarbon Cations: Structural Overview

2.8K
Cycloheptatriene is a neutral monocyclic unsaturated hydrocarbon that consists of an odd number of carbon atoms and an intervening sp3 carbon in the ring. The three double bonds in the ring correspond to 6 π electrons, which is a Huckel number, and therefore satisfies the criteria of 4n + 2 π electrons. However, the intervening sp3 carbon disrupts the continuous overlap of p orbitals. As a result, cycloheptatriene is not aromatic.
Removing one hydrogen from the intervening CH2 group...
2.8K
Criteria for Aromaticity and the Hückel 4n + 2 Rule01:20

Criteria for Aromaticity and the Hückel 4n + 2 Rule

10.5K
Like benzene, cyclobutadiene and cyclooctatetraene are cyclic compounds with alternate single and double bonds. However, their chemical behavior differs from benzene, as they are unstable and not aromatic. So, what are the structural characteristics of unsaturated compounds categorized as aromatic?  
For the first time, Eric Hückel, a German chemical physicist, derived a set of structural features for a compound to be classified as aromatic. This is now known as...
10.5K
Aromatic Hydrocarbon Anions: Structural Overview01:18

Aromatic Hydrocarbon Anions: Structural Overview

2.8K
Neutral hydrocarbons like cyclopentadiene with an odd number of carbon atoms and one intervening CH2 group in the ring are not aromatic. Cyclopentadiene with 4 π electrons does not satisfy the 4n + 2 π electron rule. Additionally, the intervening CH2 group is sp3 hybridized and lacks a vacant p orbital, thereby interrupting the overlap of p orbitals in a continuous manner and preventing the delocalization of π electrons throughout the ring.
Due to the absence of continuous...
2.8K
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry01:29

Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry

4.6K
Diels–Alder reactions between cyclic dienes locked in an s-cis configuration and dienophiles yield bridged bicyclic products.
4.6K
Nomenclature of Carboxylic Acid Derivatives: Amides and Nitriles01:11

Nomenclature of Carboxylic Acid Derivatives: Amides and Nitriles

4.0K
Naming Amides
The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
4.0K
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry01:28

Diels–Alder Reaction Forming Cyclic Products: Stereochemistry

3.9K
The Diels–Alder reaction is one of the robust methods for synthesizing unsaturated six-membered rings. The reaction involves a concerted cyclic movement of six π electrons: four π electrons from the diene and two π electrons from the dienophile.
3.9K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Pyrazine-embedded N^N^N-chelating tetracoordinate organoboron polycyclic heteroaromatics with low-lying LUMO levels and near-infrared luminescence.

Chemical science·2026
Same author

Soft supermolecule stabilized buried interface for high-performance inverted perovskite solar cells and modules.

Nature communications·2026
Same author

Interfacial Potential Compensation for HOMO Alignment in Ternary Organic Solar Cells.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Dynamic Metabolic Profiling and Diagnostic Biomarkers of Acute Graft-Versus-Host Disease Based on Metabolomics.

Biomedical chromatography : BMC·2026
Same author

Aromaticity-Localized Square Tetraboron-Extended Multiple-Resonance Emitters With B‒N Covalent Bonds for Highly Efficient Narrowband Electroluminescence.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Highly Selective Construction of D<sub>2</sub>-Symmetric Chiral Carbon Nanorings and the Diverse Assembly With Fullerenes.

Small (Weinheim an der Bergstrasse, Germany)·2026

Video Experimental Relacionado

Updated: Jun 28, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of &#945;-Imino &#947;-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

6.9K

Lactamas aromáticas tipo escalera helicoidal atada

Huidong Xie1,2, Zuo Xiao1,2, Yixiao Song1,2

  • 1Center for Excellence in Nanoscience, Key Laboratory of Nanosystem and Hierarchical Fabrication (CAS), National Center for Nanoscience and Technology, Beijing 100190, China.

Journal of the American Chemical Society
|April 16, 2024
PubMed
Resumen

Los investigadores sintetizaron nuevos lactamos aromáticos atados con estructuras helicoidales únicas. Estos compuestos exhiben capacidades de hospedaje adaptativas al huésped, particularmente para los fullerenos, y muestran potencial como emisores de luminiscencia polarizados circularmente.

Más Videos Relacionados

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
11:09

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

10.7K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.2K

Videos de Experimentos Relacionados

Last Updated: Jun 28, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of &#945;-Imino &#947;-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

6.9K
Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
11:09

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

10.7K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.2K

Área de la Ciencia:

  • Química orgánica
  • Química supramolecular
  • Ciencias de los materiales

Sus antecedentes:

  • Los aromáticos no planos atados (TNA) son una clase significativa de compuestos con propiedades únicas, pero su síntesis y características no se comprenden completamente.
  • El conocimiento existente sobre la síntesis, las estructuras y las propiedades de los TNA es limitado, lo que pone de relieve la necesidad de realizar más investigaciones.

Objetivo del estudio:

  • Para sintetizar una nueva clase de TNA, específicamente lactamos aromáticos atados, utilizando reacciones catalizadas por paladio.
  • Investigar las propiedades estructurales, de acogida y quirópticas de estos nuevos TNA.
  • Demostrar por primera vez la capacidad de acogida adaptativa de los TNA.

Principales métodos:

  • Síntesis de lactamos aromáticos atados a través de arilaciones directas intramoleculares consecutivas catalizadas por Pd.
  • Análisis estructural y de interacción huésped-invitado mediante cristalografía de rayos X, cálculos teóricos, titulación por fluorescencia y titulación por RMN.
  • Evaluación de las propiedades quirópticas y del potencial de luminiscencia polarizada circular (CPL).

Principales resultados:

  • Síntesis exitosa de lactamos aromáticos atados con sistemas conjugados tipo escalera helicoidal de hasta 13 anillos fundidos con rendimientos totales del 3,4 4,3%.
  • El lactamo sintetizado más grande, 6L-Bu-C, demostró capacidades de hospedaje adaptativas sin precedentes, con su cavidad adaptándose a los huéspedes fullerenos.
  • Se observó una afinidad de unión más fuerte de 6L-Bu-C para C70 sobre C60, atribuida a interacciones π-π convexas-cóncavas mejoradas.
  • Se observaron propiedades quirópticas distintas y persistentes tanto para los enantiómeros P como para los M.

Conclusiones:

  • Los lactamos aromáticos atados representan una clase novedosa y sintéticamente accesible de TNA con estructuras helicoidales complejas.
  • Estos compuestos exhiben notables capacidades de adaptación al huésped, allanando el camino para nuevas aplicaciones supramoleculares.
  • Las distintas propiedades quirópticas de los TNA enantiopuros resaltan su potencial como eficientes emisores de luminiscencia polarizados circularmente.