Video Experimental Relacionado

Updated: Jun 27, 2025

Recapitulation of an Ion Channel IV Curve Using Frequency Components
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Recapitulation of an Ion Channel IV Curve Using Frequency Components

Published on: February 8, 2011

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Dinámica hERG mediada por CAVIN1: un nuevo mecanismo que subyace a la variabilidad interindividual en la TQ larga

Zeina R Al Sayed1, Céline Pereira1, Rémi Le Borgne2

  • 1PARCC, INSERM (Z.R.A.S., C.P., C.J., N.M., J.-S.H.), Université Paris Cité, Paris, France.

Circulation
|April 29, 2024
PubMed
Resumen

La susceptibilidad a la prolongación del intervalo QT inducida por fármacos (diLQT) está relacionada con la dinámica del canal hERG. CAVIN1 regula la translocación del canal hERG, lo que influye en la sensibilidad del paciente a los medicamentos que prolongan el intervalo QT.

Palabras clave:
Caveolasefectos secundarios y reacciones adversas relacionados con el medicamentocélulas madre pluripotentes inducidassíndrome del intervalo QT largoMiocitos cardíacos

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