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Updated: Jun 26, 2025

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Spexin disminuye la vulnerabilidad a la fibrilación auricular actuando sobre el receptor de galanina 2

Desheng Li1, Yang Liu2, Changzhu Li1

  • 1National Key Laboratory of Frigid Zone Cardiovascular Diseases, Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education, International Cooperation Base for Major Cardiovascular Diseases in Cold Regions, China) College of Pharmacy (D.L., Changzhu Li, Z.Z., K.G., H.B., J.Y., K.S., L. Zhang, J.L., Chenhong Li, J.S., L. Zhao, Y.P., L.X., Y.Z., Y. Lu, B.Y., Z.P.), First Affiliated Hospital, Harbin Medical University, China.

Circulation
|May 10, 2024
PubMed
Resumen

Spexin, un nuevo ligando, reduce la susceptibilidad a la fibrilación auricular inhibiendo la fosforilación de CREB a través del receptor GALR2. Esta vía desregula los genes clave, ofreciendo un nuevo objetivo terapéutico para la FA.

Palabras clave:
El CREBLos demásNúmero de servicioFibrilación auricularreceptores de la galaninalas especificaciones

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