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Respuesta al virus del chikungunya en el oeste de África

Respuesta al virus del chikungunya en el oeste de África

Martin Faye ¹, Xavier Berthet ¹, Nicholas Di Paola ², Ousmane Faye ¹, Amadou Alpha Sall ¹, Abdourahmane Sow ¹

Martin Faye ¹, Xavier Berthet ¹, Nicholas Di Paola ²

¹Institut Pasteur de Dakar, Dakar 220, Senegal.
²Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MA, USA.

⁰Institut Pasteur de Dakar, Dakar 220, Senegal.

Lancet (London, England) +

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18 de mayo de 2024

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Resumen

No abstract available on PubMed

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Cross-reactivity

Cross-reactivity

Overview

The ability of a single antibody to recognize multiple structurally similar epitopes is an important immune defense strategy that enables the host to efficiently defend against many potentially threatening pathogens. However, cross-reactivity also elicits allergy symptoms against related allergens. It is increasingly important to understand the principles of cross-reactivity, as antibodies are actively being developed as therapeutic modalities for diverse diseases, including cancer.

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