Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Teratogenicity01:07

Teratogenicity

2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

919
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
919
Ovarian Cycle01:27

Ovarian Cycle

1.1K
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
1.1K
Proliferative Phase01:20

Proliferative Phase

452
The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
452
Development of Blood Vessels01:07

Development of Blood Vessels

567
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
567
Oogenesis02:07

Oogenesis

63.6K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.6K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Insulin resistance and type 2 diabetes as allostatic responses to chronic nutrient excess.

Cell metabolism·2026
Same author

Lipidomic profiling reveals a distinct lipidomic signature of early gestational diabetes.

Communications medicine·2026
Same author

Prophylactic Dextrose Gel for Neonatal Hypoglycemia and Neurocognitive Function at 6 to 7 Years of Age: A Secondary Analysis of a Randomized Clinical Trial.

JAMA pediatrics·2026
Same author

Maternal butyrate administration ameliorates fetal fatty liver and maternal metabolic alterations related to maternal obesity.

Molecular and cellular endocrinology·2026
Same author

Budesonide and Surfactant Therapy Versus Surfactant Alone on Incidence of Lung Disease in Preterm Infants (BEST Lung): Study Protocol for a Systematic Review and Individual Participant Data Meta-Analysis With Nested Prospective Meta-Analysis.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same author

A longitudinal study of partner support and maternal mental health following pregnancy during public health crises.

Journal of affective disorders·2026

Video Experimental Relacionado

Updated: Jun 23, 2025

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
06:49

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

1.7K

Fisiopatología desde la preconcepción, durante el embarazo y después

Marie-France Hivert1, Helena Backman2, Katrien Benhalima3

  • 1Division of Chronic Disease Research Across the Lifecourse (CoRAL), Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA; Diabetes Unit, Massachusetts General Hospital, Boston, MA, USA.

Lancet (London, England)
|June 23, 2024
PubMed
Resumen

La diabetes gestacional, la complicación más común del embarazo, es más compleja de lo que se pensaba. Comprender sus subtipos y cambios metabólicos tempranos es clave para prevenir complicaciones maternas e infantiles.

Más Videos Relacionados

Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
07:51

Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface

Published on: May 21, 2015

17.2K
Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

802

Videos de Experimentos Relacionados

Last Updated: Jun 23, 2025

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
06:49

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

1.7K
Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
07:51

Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface

Published on: May 21, 2015

17.2K
Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

802

Área de la Ciencia:

  • Obstetricia y ginecología
  • Endocrinología
  • Medicina perinatal

Sus antecedentes:

  • La diabetes mellitus gestacional (DMG) es la complicación médica más frecuente durante el embarazo.
  • Históricamente, el manejo de GDM se centró en el control glucémico a finales del segundo trimestre.
  • La evidencia emergente destaca la influencia de los factores previos al embarazo y específicos del embarazo, incluidas las funciones no glucémicas, en la etiología y los resultados de la DMG.

Objetivo del estudio:

  • Desafiar la visión tradicional de la diabetes gestacional.
  • Explorar la heterogeneidad de la DMG basada en el tiempo y la fisiopatología.
  • Investigar el impacto de las perturbaciones metabólicas tempranas en el desarrollo materno y fetal.

Principales métodos:

  • Revisión de la evidencia reciente sobre la fisiopatología de la diabetes gestacional.
  • Análisis de los factores que influyen en la glucemia gestacional.
  • Examen de la secreción de insulina y de los patrones de resistencia al principio y al final del embarazo.

Principales resultados:

  • La diabetes gestacional exhibe heterogeneidad, con distintos subtipos tempranos y resistentes a la insulina.
  • Los cambios metabólicos tempranos de la DMG pueden perjudicar el desarrollo de la placenta y afectar el crecimiento fetal.
  • Los subtipos específicos de DMG están relacionados con un mayor riesgo de complicaciones durante el embarazo.

Conclusiones:

  • Una comprensión más profunda de la fisiopatología y la heterogeneidad de la DMG es crucial.
  • Se necesitan nuevas estrategias de manejo para prevenir complicaciones a corto y largo plazo para las madres y la descendencia.
  • Las intervenciones deben abarcar los períodos previos a la concepción, el embarazo y el posparto.