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Updated: Jun 18, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

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Una reacción general de tres componentes de alquilo petasa de boro-Mannich

Chao Hu1, Jet Tsien1, Si-Jie Chen2

  • 1Department of Biochemistry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390, United States.

Journal of the American Chemical Society
|July 29, 2024
PubMed
Resumen

Este estudio introduce una nueva reacción de tres componentes para sintetizar aminas complejas ricas en C ((sp3), cruciales para el descubrimiento de fármacos. El método permite la generación rápida de diversas bibliotecas de aminas para identificar posibles candidatos a fármacos.

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