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Updated: Jun 14, 2025

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
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La CDK5-ciclina B1 regula la fidelidad mitótica

Xiao-Feng Zheng1, Aniruddha Sarkar1, Humphrey Lotana2

  • 1Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

Nature
|September 4, 2024
PubMed
Resumen

La cinasa dependiente de ciclina 5 (CDK5) es activa en la mitosis y es esencial para la fidelidad de la división celular. La ciclina B1 se asocia con la CDK5, formando un complejo que asegura una replicación celular precisa.

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