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Updated: Jun 11, 2025

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Bases estructurales de la descomposición del ARNm por el supercomplejo exosoma-ribosoma humano

Alexander Kögel1, Achim Keidel1, Matina-Jasemi Loukeri1

  • 1Department of Structural Cell Biology, Max Planck Institute of Biochemistry, Martinsried, Germany.

Nature
|October 9, 2024
PubMed
Resumen

El exosoma citoplasmático y el ribosoma forman un supercomplejo para la descomposición del ARNm. Esta estructura acopla directamente la helicasa SKI2 al exosoma, enhebrando el ARN para la degradación durante la traducción.

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