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Updated: Jun 8, 2025

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

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Evolución continua de genes definidos por el usuario a 1 millón de veces la tasa de mutación genómica

Gordon Rix1, Rory L Williams2, Vincent J Hu2

  • 1Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92617, USA.

Science (New York, N.Y.)
|November 7, 2024
PubMed
Resumen

Los investigadores aceleraron la evolución genética utilizando sistemas mejorados de replicación de ADN ortogonal (OrthoRep) en levaduras. Este método generó rápidamente diversas secuencias de genes, revelando restricciones evolutivas y permitiendo aplicaciones de ingeniería biomolecular.

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