Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

49.0K
Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
49.0K
Network Covalent Solids02:18

Network Covalent Solids

13.4K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
13.4K
Crystal Field Theory - Octahedral Complexes02:58

Crystal Field Theory - Octahedral Complexes

26.2K
Crystal Field Theory
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
26.2K
Crystal Field Theory - Tetrahedral and Square Planar Complexes02:46

Crystal Field Theory - Tetrahedral and Square Planar Complexes

41.5K
Tetrahedral Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...
41.5K
Adaptability of Cytoskeletal Filaments01:12

Adaptability of Cytoskeletal Filaments

3.7K
The cytoskeleton is a complex dynamic structure performing varied functions based on cellular requirements. The adaptability of the individual filaments in the cytoskeleton determines their ability to perform various functions within the cell. It can undergo rapid reorganization during processes like cell division or remain stable for several hours as in the interphase. The adaptability of these filaments depends on stringent regulatory mechanisms. The microfilament and microtubules of the...
3.7K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

4.8K
Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
4.8K

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Two-coordinate Cu(I) sites in ZIF-derived porous carbon enable high CO working capacity for CO/N₂ separation.

Nature communications·2026
Same author

Versatile vector tools for efficient protein screening across multiple expression systems.

FEBS open bio·2026
Same author

PbSe/WTe<sub>2</sub> Schottky Heterojunction for Low-Noise Mid-Infrared Detection.

ACS applied materials & interfaces·2026
Same author

Localised Autophagy Inhibition by Nanodiamonds Potentiates Arsenic Therapy With Favourable Safety Profile in Solid Tumours.

Cell proliferation·2026
Same author

Molecular Probing in a Metal-Organic Framework for Selective Gas Adsorption and Separation.

Journal of the American Chemical Society·2026
Same author

Synaptic Plasticity as a Mechanism of Opioid Tolerance and Hyperalgesia.

Biology·2026

Video Experimental Relacionado

Updated: Jun 6, 2025

Microfluidic-based Synthesis of Covalent Organic Frameworks COFs: A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface
08:42

Microfluidic-based Synthesis of Covalent Organic Frameworks COFs: A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface

Published on: July 10, 2017

13.3K

Marco orgánico covalente dinámico de un solo cristal para las alineaciones de huéspedes adaptativos

Shan Liu1, Lei Wei1, Tengwu Zeng1

  • 1School of Physical Science and Technology, Shanghai Key Laboratory of High-Resolution Electron Microscopy, State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai 201210, China.

Journal of the American Chemical Society
|November 30, 2024
PubMed
Resumen

Los marcos orgánicos covalentes dinámicos 3D (COF) exhiben la inclusión adaptativa del huésped a través del movimiento molecular. Este estudio revela la dinámica a nivel atómico y vías específicas que permiten la flexibilidad del marco para las esponjas moleculares.

Más Videos Relacionados

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.2K
Author Spotlight: Accelerating Discovery in Microporous Material Chemistry
07:20

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

Published on: October 6, 2023

3.5K

Videos de Experimentos Relacionados

Last Updated: Jun 6, 2025

Microfluidic-based Synthesis of Covalent Organic Frameworks COFs: A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface
08:42

Microfluidic-based Synthesis of Covalent Organic Frameworks COFs: A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface

Published on: July 10, 2017

13.3K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.2K
Author Spotlight: Accelerating Discovery in Microporous Material Chemistry
07:20

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

Published on: October 6, 2023

3.5K

Área de la Ciencia:

  • Ciencias de los materiales
  • La cristalografía
  • Química supramolecular

Sus antecedentes:

  • Los marcos orgánicos covalentes dinámicos 3D (COF) muestran cambios estructurales con las moléculas invitadas.
  • Los mecanismos precisos de la flexibilidad de COF y la adaptación de los huéspedes no se comprenden completamente.

Objetivo del estudio:

  • Proporcionar información a nivel atómico sobre la dinámica de COF-300 durante la inclusión de invitados.
  • Elucidar la movilidad conformacional y la adaptabilidad huésped-huésped en los COF dinámicos.

Principales métodos:

  • Crecimiento de un solo cristal de COF-300 utilizando un protocolo de transiminación por gradiente de difusión.
  • Difracción de rayos X de alta resolución para el análisis estructural.
  • Análisis cuantitativo de energía de las transformaciones estructurales.

Principales resultados:

  • Dinámica de rotación y traslación observada de los enlaces iminos y las unidades fenílicas en COF-300.
  • Ángulos de torsión de conmutación identificados en motivos de dimina de tereftalaldehído.
  • Fases intermedias metastables descubiertas durante la evolución estructural.
  • Se ha demostrado la adaptación del marco a diversas moléculas huéspedes con diversas alineaciones.

Conclusiones:

  • La movilidad conformacional en los COF es impulsada por dinámicas moleculares específicas, no por movimientos arbitrarios.
  • Los COF dinámicos se pueden diseñar como esponjas moleculares para estudiar estructuras líquidas.
  • Las vías observadas se asemejan al plegamiento de proteínas, lo que sugiere un comportamiento dinámico predecible.