Video Experimental Relacionado

Updated: Jun 3, 2025

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
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Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Published on: March 1, 2015

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Evaluación de la disfagia y sus asociaciones en pacientes con esclerosis múltiple secundaria progresiva

Majid Hamidi1, Nasim Rezaeimanesh1, Mohammad Ali Sahraian1

  • 1Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Sina Hospital, Hasan Abad Sq., Tehran, Iran.

Multiple sclerosis and related disorders
|January 10, 2025
PubMed

En este estudio transversal en pacientes con esclerosis múltiple secundaria progresiva que recibían anticuerpos monoclonales anti-CD20, evaluamos la presencia de disfagia y analizamos su asociación con el sexo, la edad, la duración de la enfermedad, la gravedad de la discapacidad y las terapias modificadoras de la enfermedad (TME). Se utilizó la versión validada en persa del cuestionario Dysphagia in Multiple Sclerosis (DYMUS). Se incluyó un total de 66 pacientes. La mediana de la puntuación DYMUS fue de 1,0 [rango intercuartílico: 0,0-2,3] y 40 (60,6 %) presentaron un DYMUS positivo. Solo las TME mostraron una asociación significativa con la puntuación DYMUS; los pacientes que recibieron rituximab presentaron puntuaciones más altas (diferencia media estimada: 0,96 (±0,39), p = 0,014). Al agrupar a los pacientes según puntuaciones DYMUS positivas y negativas, no se observaron asociaciones significativas (p > 0,05).

Palabras clave:
DYMUSDisfagiaOcrelizumabRituximabEsclerosis múltiple secundaria progresiva

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