Video Experimental Relacionado

Updated: May 6, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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Síntesis asimétrica total de las asperonas A y B a través de la quinona organocatalizada [5 + 2]

Chunlei Qu1, Lu Chen1, Peng Wang1

  • 1State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Frontiers Science Center for New Organic Matter, Nankai University, Tianjin 300071, China.

Journal of the American Chemical Society
|February 13, 2025
PubMed
Resumen

Los investigadores lograron la primera síntesis total asimétrica de las policetidas antiinflamatorias asperonas A y B. Los pasos clave involucraron reacciones de Diels-Alder y cicloadición organocatalizada para construir sus estructuras centrales.

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