Video Experimental Relacionado
Updated: May 27, 2025
09:32
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
7.1K
Dermatitis atópica
Emma Guttman-Yassky1, Yael Renert-Yuval2, Patrick M Brunner1
1Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lancet (London, England)
|February 15, 2025
Resumen
La dermatitis atópica, una afección crónica común de la piel, causa picazón severa y afecta la calidad de vida. Los avances recientes en la comprensión de su fisiopatología han llevado a nuevos tratamientos específicos que ofrecen un mejor control de la enfermedad.
Área de la Ciencia:
- Dermatología
- Inmunología
- Alergias
Sus antecedentes:
- La dermatitis atópica es una enfermedad inflamatoria crónica de la piel prevalente en todo el mundo.
- Se caracteriza por erupciones eczemáticas y picazón intensa, reduciendo significativamente la calidad de vida del paciente, particularmente en casos de moderado a severo.
- La dermatitis atópica está asociada con otras afecciones atópicas que afectan a los sistemas respiratorio y gastrointestinal.
Objetivo del estudio:
- Para discutir la comprensión fisiopatológica actualizada de la dermatitis atópica.
- Revisar el panorama terapéutico en evolución para el manejo de esta condición.
- Para resaltar nuevos enfoques de tratamiento dirigido.
Principales métodos:
- Revisión de la literatura científica más reciente.
- Análisis de las directrices de tratamiento actuales.
- Discusión de las estrategias terapéuticas emergentes.
Principales resultados:
- Los tratamientos tradicionales se basaron en amplios agentes inmunosupresores, lo que plantea desafíos para el control a largo plazo.
- Los avances recientes han mejorado la comprensión de la fisiopatología de la dermatitis atópica.
- Se han desarrollado y aprobado nuevos tratamientos específicos, que ofrecen opciones más seguras y efectivas.
Conclusiones:
- Los conocimientos fisiopatológicos mejorados han revolucionado el tratamiento de la dermatitis atópica.
- Las nuevas terapias dirigidas representan un avance significativo con respecto a los inmunosupresores generales más antiguos.
- El panorama terapéutico en evolución ofrece mejores perspectivas para los pacientes con dermatitis atópica.
Videos de Conceptos Relacionados
01:23Skin Diseases and Disorders
2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.8K
01:21Accessory Structures of the Skin: Sebaceous Glands
1.7K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
1.7K
01:20Asthma: Pathogenesis and Management
339
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
339
01:26Asthma-II: Pathophysiology and Classification
2.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.6K
02:06Allergic Reactions
27.2K
Overview
27.2K
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.7K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.7K