Video Experimental Relacionado
Updated: Aug 17, 2026
07:25
Optogenetic Activation of Zebrafish Somatosensory Neurons using ChEF-tdTomato
Published on: January 31, 2013
Inducción de proyecciones funcionales de la retina hacia el sistema somatosensorial
Nature
|September 12, 1985
Resumen
Los axones ópticos pueden formar conexiones funcionales en el tálamo somatosensorial. Este estudio muestra que la información visual puede ser procesada por la corteza somatosensorial, lo que demuestra la plasticidad neural.
Área de la Ciencia:
- La neurociencia es la neurociencia.
- La neurobiología es la neurobiología.
- Los sistemas sensoriales son sistemas sensoriales.
Sus antecedentes:
- Los axones ópticos normalmente se proyectan hacia los núcleos tálamicos visuales.
- Las primeras proyecciones a los núcleos tálamicos no visuales (MG, VB) son transitorias.
- Las conexiones retinotópicas permanentes se pueden inducir en MG y VB mediante la eliminación de objetivos y la creación de espacio.
Objetivo del estudio:
- Para determinar si las proyecciones retino-VB inducidas experimentalmente son funcionales.
- Investigar el potencial de la plasticidad intermodal en el tálamo y la corteza.
Principales métodos:
- Hamsters sirios recién nacidos se sometieron a una cirugía para crear proyecciones permanentes de retino-VB.
- Se realizaron grabaciones neurofisiológicas en las cortes somatosensoriales (SI, SII) de animales maduros.
- Se utilizaron estímulos visuales para evocar respuestas en SI y SII.
Principales resultados:
- La estimulación visual evocó de manera confiable respuestas de varias unidades en SI y SII de hámsters operados.
- Los hámsters operados mostraron representaciones parcialmente retinotópicas del campo visual en SI y SII.
- Los hámsters normales no exhibieron estas respuestas visuales en SI y SII.
Conclusiones:
- Los axones del tracto óptico pueden formar sinapsis funcionales dentro del núcleo somatosensorial del tálamo (VB).
- Las estructuras neuronales pueden mediar funciones para modalidades sensoriales distintas de su principal.
- Esto demuestra un potencial significativo para la plasticidad neuronal intermodal.
Videos de Conceptos Relacionados
01:32The Retina
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
01:24Vision
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
01:33Somatosensation
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
01:11Sensory Perception: Organization of the Somatosensory System
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
01:29Overview of Somatic Sensory Pathways
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
01:28Major Somatic Sensory Pathways
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the posterior columns...