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Seguridad del etripamil administrado por vía intranasal: actualización del ensayo RAPID

Bruce S Stambler1, A John Camm2, Jonathan P Piccini3

  • 1Piedmont Heart Institute, Atlanta, GA, USA.

Lancet (London, England)
|May 10, 2025
PubMed
Resumen

No abstract available in PubMed .

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The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
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