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Las formas del equilibrio STAT5 y STAT3 muestran la función de las células dendríticas y la inmunidad tumoral

Jiajia Zhou1,2, Kole Tison1,2,3,4, Haibin Zhou5

  • 1Department of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.

Nature
|May 14, 2025
PubMed
Resumen

La eficacia del bloqueo del punto de control inmune (ICB) se basa en las células dendríticas. Una nueva investigación revela que la interacción de las vías STAT3 y STAT5 en las células dendríticas es clave para el éxito de la ICB, y los degradantes de STAT3 son prometedores en el tratamiento del cáncer.

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