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Las citoquinas de tipo 2 actúan sobre las neuronas sensoriales entéricas para regular la defensa del huésped

Rocky M Barilla1,2, Clara Berard1, Linyu Sun1

  • 1Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Science (New York, N.Y.)
|May 22, 2025
PubMed
Resumen

Las citoquinas de tipo 2 aumentan la neuromedina U (NMU) y el péptido β relacionado con el gen de la calcitonina (CGRPβ) en las neuronas entéricas, mejorando la defensa del huésped contra las infecciones de helmintos. Esto pone de relieve la comunicación neuroinmune crucial en el intestino.

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