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Updated: Sep 15, 2025

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La duplicación del genoma en curso da forma a la evolución y la inmunidad en el cáncer de ovario

Andrew McPherson1,2, Ignacio Vázquez-García3,4,5,6,7, Matthew A Myers3,4

  • 1Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. mcphera1@mskcc.org.

Nature
|July 16, 2025
PubMed
Resumen

La duplicación de todo el genoma (WGD) impulsa la evolución del cáncer y la evasión inmune en los tumores ováricos. Este proceso en curso afecta la diversidad tumoral, la inestabilidad cromosómica y la supresión inmune, revelando nuevos objetivos terapéuticos.

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