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Updated: Sep 10, 2025

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TRAF6 ejerce efectos promotores de tumores a través de la modulación genética y autofágica en el cáncer gástrico

Yifan Zou1,2, Zhenguang Mao2,3, Jianghao Xu1

  • 1Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Molecular carcinogenesis
|August 20, 2025
PubMed
Resumen

Las variantes genéticas en la autofagia, específicamente TRAF6 rs5030437 G>A, están relacionadas con un mayor riesgo de cáncer gástrico. La expresión del gen TRAF6 afecta la inmunidad tumoral y promueve el crecimiento de las células cancerosas, ofreciendo nuevos conocimientos sobre el desarrollo del cáncer gástrico.

Palabras clave:
La autofagiaCáncer gástricoLas variantes genéticasSusceptibilidadmicroambiente del tumor

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