Video Experimental Relacionado
Updated: Sep 8, 2025
09:57
How to Measure Cortical Folding from MR Images: a Step-by-Step Tutorial to Compute Local Gyrification Index
Published on: January 2, 2012
28.1K
Asociación entre la educación urbana y la girificación cortical en personas con esquizofrenia
Vittal Korann1,2, Umesh Thonse3, Arpitha Jacob4
1Schizophrenia Division, Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.
Indian journal of psychological medicine
|August 20, 2025
Resumen
La educación urbana influye en el desarrollo del cerebro, aumentando potencialmente el riesgo de esquizofrenia. Este estudio encontró que la urbanización se correlaciona con cambios de giro cortical en regiones específicas del cerebro, destacando los impactos ambientales en el desarrollo neurológico.
Área de la Ciencia:
- La neurociencia
- La psiquiatría
- Estudios urbanos
Sus antecedentes:
- La educación urbana está relacionada con un mayor riesgo de esquizofrenia.
- Los cambios cerebrales subyacentes asociados con los entornos urbanos no se comprenden bien.
- La girificación cortical, un marcador del desarrollo temprano del cerebro, se explora en relación con la urbanización.
Objetivo del estudio:
- Investigar la influencia de la educación urbana en la giración cortical.
- Para identificar regiones específicas del cerebro afectadas por la vida urbana.
- Comprender los factores ambientales que contribuyen a los cambios en el desarrollo neurológico.
Principales métodos:
- Se incluyeron 70 controles sanos y 87 pacientes con esquizofrenia (18-50 años).
- Datos recopilados de lugares de nacimiento y crianza, categorizados utilizando datos del censo.
- Calculó un índice de urbanización y analizó las imágenes de resonancia magnética del cerebro para el índice de girificación (GI).
Principales resultados:
- Se encontró una asociación positiva entre el índice de urbanización y el giro gastrointestinal en el giro supramarginal izquierdo, el giro frontal medio rostral izquierdo y el giro occipital lateral.
- Se observaron efectos significativos de interacción entre el diagnóstico de esquizofrenia y la urbanización en múltiples regiones cerebrales.
- La giración cortical está significativamente influenciada por el grado de crianza urbana.
Conclusiones:
- La vida urbana impacta significativamente el desarrollo del cerebro.
- Comprender estas influencias ambientales es crucial para la prevención de la esquizofrenia.
- Los resultados pueden servir de base para la planificación urbana y las estrategias de salud pública.
Videos de Conceptos Relacionados
01:29Psychological and Sociocultural Causes of Schizophrenia
185
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
185
01:29Biological Causes of Schizophrenia
145
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
145
01:17Schizophrenia
215
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
215
01:27Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
941
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
941
01:21Association Areas of the Cortex
6.2K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
6.2K
01:30Negative and Cognitive Symptoms of Schizophrenia
118
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
118