Alucinaciones visuales debidas a la retirada de baclofeno por vía oral
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Ver abstracta en PubMed
Resumen
Este resumen es generado por máquina.La interrupción brusca de la administración oral de baclofeno (agonista del receptor GABA B) en pacientes con lesión de la médula espinal puede causar síntomas de abstinencia como desorientación y alucinaciones. La reintroducción del baclofeno resolvió estos efectos adversos.
Área De La Ciencia
- Neurología
- Farmacología
Sus Antecedentes
- El baclofeno es un agonista del receptor B del ácido gamma-aminobutírico (GABA).
- Se prescribe comúnmente para el tratamiento de la espasticidad en pacientes con lesión de la médula espinal (LME).
- El baclofeno puede administrarse por vía oral o intratecal.
Objetivo Del Estudio
- Para resaltar el riesgo potencial de síndrome de abstinencia de baclofeno.
- Para reportar un caso de síntomas de abstinencia de baclofeno en un paciente con LME.
Principales Métodos
- Un estudio de caso de un hombre de 62 años con LME.
- El paciente estaba tomando baclofeno por vía oral para la espasticidad.
- Se interrumpió el tratamiento con baclofeno debido a una proctosigmoiditis y el paciente fue monitoreado para detectar efectos adversos.
Principales Resultados
- El paciente desarrolló desorientación y alucinaciones después de la interrupción del tratamiento con baclofeno.
- Estos síntomas neurológicos desaparecieron tras la reintroducción del baclofeno oral.
- Esto sugiere un posible síndrome de abstinencia de baclofeno.
Conclusiones
- La interrupción brusca de la administración oral de baclofeno puede precipitar los síntomas de abstinencia.
- Los médicos deben estar al tanto del síndrome de abstinencia de baclofeno en pacientes con LME.
- Puede ser necesario un manejo cuidadoso y una disminución gradual al suspender el tratamiento con baclofeno.
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