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Disorders of the Nervous Tissue01:28

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
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The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
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The nervous system, responsible for sensing, integrating, and responding to various stimuli, is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The PNS has two functional divisions: the sensory or afferent division and the motor or efferent division.
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Video Experimental Relacionado

Updated: Sep 10, 2025

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
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Trastornos neurológicos funcionales: una revisión completa

Lakshmi Priya Lalitha1, Purushottam T Acharya2, Mahendra Javali2

  • 1Assistant Professor, Department of Neurology, M S Ramaiah Medical College, Bengaluru, Karnataka, India, Corresponding Author, Orcid: https://orcid.org/0000-0003-0165-5570.

The Journal of the Association of Physicians of India
|August 21, 2025
PubMed
Resumen

Trastornos neurológicos funcionales (TNF) con síntomas inconsistentes con las condiciones neurológicas. El diagnóstico precoz con signos clínicos positivos y el tratamiento multidisciplinario son cruciales para el bienestar del paciente.

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Área de la Ciencia:

  • Neurología
  • La neurociencia

Sus antecedentes:

  • Los trastornos neurológicos funcionales (TNF) implican síntomas no explicados por afecciones neurológicas reconocidas.
  • Históricamente, la comprensión de los FND ha evolucionado significativamente, desde atribuciones sobrenaturales hasta los modelos actuales de disfunción de los neurocircuitos.
  • Los FND representan una parte sustancial de las consultas neurológicas, lo que pone de relieve la necesidad de enfoques diagnósticos precisos.

Objetivo del estudio:

  • Revisar la evolución de la comprensión y la terminología del FND.
  • Describir los signos clínicos clave para el diagnóstico de varios subtipos de FND.
  • Hacer hincapié en la importancia de los signos diagnósticos positivos en el tratamiento de la EPN.

Principales métodos:

  • Revisión de la literatura histórica y actual sobre trastornos neurológicos funcionales.
  • Categoría de las ENF en subtipos específicos (por ejemplo, debilidad funcional de las extremidades, convulsiones, trastornos del movimiento).
  • Identificación y discusión de las claves clínicas de diagnóstico para cada subtipo de FND.

Principales resultados:

  • Los FND abarcan diversas presentaciones que incluyen debilidad funcional de las extremidades, convulsiones, movimiento, marcha, pseudo-sincopía y disfunción cognitiva.
  • Los signos clínicos positivos son esenciales para el diagnóstico seguro de FND, yendo más allá de un diagnóstico de exclusión.
  • La identificación temprana de las señales positivas ayuda a una investigación juiciosa y a una gestión oportuna.

Conclusiones:

  • El diagnóstico preciso de las FND se basa en la identificación de signos clínicos positivos específicos.
  • Un enfoque multidisciplinario, incluida la comunicación, el manejo de la comorbilidad psiquiátrica y la terapia personalizada, es vital para un manejo eficaz de la FND.
  • La investigación continua sobre la disfunción de los neurocircuitos está en curso para estos trastornos complejos.