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Tormenta eléctrica en pacientes con miocardiopatía hipertrófica

Pierre Groussin¹, Melvyn Dezecot¹, Donovan Decaudin¹

¹University of Rennes, Centre Hospitalier Universitaire (CHU) Rennes, INSERM, LTSI-UMR 1099, Rennes, France.

JACC. Clinical electrophysiology

|August 21, 2025

Resumen

La tormenta eléctrica (ES) en pacientes con miocardiopatía hipertrófica (HCM) a menudo requiere medicamentos antiarrítmicos, pero con frecuencia conduce a recurrencias de arritmia ventricular (VA). Los resultados a largo plazo son pobres, con una mortalidad significativa dentro de los 18 meses.

Área de la Ciencia:

Cardiología
Electrofisiología
Medicina cardiovascular

Sus antecedentes:

El manejo de la tormenta eléctrica (ES) en la cardiomiopatía hipertrófica (HCM) no está bien definido.
Los pacientes con CMH tienen un alto riesgo de sufrir arritmias ventriculares (AV).

Objetivo del estudio:

Analizar el manejo agudo de la ES en pacientes con CMH.
Evaluar los resultados hospitalarios y a largo plazo de los pacientes con CMH que presentan ES.

Principales métodos:

Estudio multicéntrico retrospectivo de 23 pacientes con CMH con ES (2017-2023).
Se recogieron datos demográficos, antecedentes de AV, tratamientos (medicamentos antiarrítmicos, ablación por catéter de radiofrecuencia) y resultados.

Principales resultados:

La mayoría de los AV fueron taquicardias ventriculares monomórficas; se usaron comúnmente amiodarona y beta-bloqueantes.
La ablación por catéter de radiofrecuencia se realizó en el 44% de los pacientes, pero no se asoció con mejores resultados.
Se observaron altas tasas de recurrencia de AV (30%) y mortalidad (9% en el hospital, 18% a los 18 meses).

Conclusiones:

La ES en pacientes con CMH a menudo requiere medicamentos antiarrítmicos, pero se asocia con recurrencias frecuentes de AV.
Los resultados a largo plazo para los pacientes con CMH con ES son pobres, con una mortalidad significativa.
Se necesitan más investigaciones para optimizar los resultados de la ablación por radiofrecuencia en esta población.

Palabras clave:

Ablación por catéter tormenta eléctrica cardiomiopatía hipertrófica Disminución del ritmo ventricular

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