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Soledad y depresión en pacientes con LES: un estudio transversal en una muestra brasileña
Valentina Garofani Ramos1, Maria Eduarda Pelaez de Campos1, Thelma Skare1
1Mackenzie Evangelical School of Medicine, Curitiba, Brazil.
Journal of psychosomatic research
|August 21, 2025
Resumen
Los niveles de soledad en pacientes con lupus eritematoso sistémico (LES) son similares a los controles y se correlacionan con la depresión. La soledad no se asoció con la actividad de la enfermedad o el daño en pacientes con LES.
Área de la Ciencia:
- Reumatología
- Psicología
- Salud pública
Sus antecedentes:
- Las enfermedades crónicas como el lupus eritematoso sistémico (LES) pueden aumentar el riesgo de soledad.
- La soledad puede afectar negativamente el estado clínico de los pacientes con enfermedades crónicas.
Objetivo del estudio:
- Para evaluar la soledad en pacientes con LES en comparación con los controles.
- Examinar la asociación entre la soledad y la depresión, la actividad de la enfermedad y el daño en pacientes con LES.
Principales métodos:
- 109 pacientes con LES y 92 controles completaron escalas validadas para la depresión (CES-D), la soledad (UCLA-BR), la actividad de la enfermedad (SLEDAI) y el daño (SLICC/ ACR DI).
- También se recogieron variables clínicas y epidemiológicas.
Principales resultados:
- Los pacientes con LES informaron más síntomas depresivos que los controles, pero puntuaciones de soledad similares.
- La soledad se correlacionó fuertemente con la depresión tanto en los pacientes con LES como en los controles.
- No se encontraron asociaciones significativas entre la soledad y la actividad de la enfermedad del LES, el daño acumulado o la duración de la enfermedad.
- Las peores percepciones de las relaciones familiares se relacionaron con un aumento de la soledad en los pacientes con LES.
Conclusiones:
- Los niveles de soledad son comparables entre los pacientes con LES y los controles.
- La depresión es un correlato significativo de la soledad en ambos grupos.
- La soledad en pacientes con LES no está asociada con la actividad de la enfermedad, el daño acumulado de órganos o las variables clínicas.
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