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Hiperinfección de Strongyloides tratada con ivermectina subcutánea en un paciente con un error congénito de inmunidad

Peter Conlon¹, Fergal Howley¹, Dana Al Sharqi²

¹Department of Infectious Diseases, Beaumont Hospital, Dublin, Ireland.

The American journal of tropical medicine and hygiene

|August 21, 2025

Resumen

La hiperinfección por Strongyloides es difícil de diagnosticar y tratar, especialmente en pacientes con deficiencias inmunológicas. Este caso destaca la ivermectina subcutánea como una opción de tratamiento viable para casos graves de malabsorción.

Área de la Ciencia:

Parasitología médica
Inmunología
Enfermedades infecciosas

Sus antecedentes:

El síndrome de hiperinfección por Strongyloides (SHS, por sus siglas en inglés) es una afección potencialmente fatal, generalmente asociada con inmunodeficiencia secundaria.
El diagnóstico de SHS puede ser difícil debido a las limitaciones en la microscopía y la serología, particularmente en la hipogammaglobulinemia.
La ivermectina oral es el tratamiento estándar, pero su eficacia se ve comprometida por la malabsorción.

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