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Predictores de no llegada a las visitas iniciales de detección del estudio entre adultos negros: datos de los ensayos
Benjamin Grobman1, Christian Rivera1, Mingyu Zhang1
1Harvard Medical School, Boston, MA, United States of America; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States of America.
Contemporary clinical trials
|August 21, 2025
Resumen
Los participantes mayores eran más propensos a asistir a las visitas iniciales al estudio. Factores como el tamaño más grande de la familia y los retrasos más largos entre los contactos y las visitas se relacionaron con la no llegada, lo que afectó el éxito del reclutamiento del ensayo.
Área de la Ciencia:
- Ensayos clínicos
- Intervenciones de salud pública
- Disparidades en materia de salud
Sus antecedentes:
- La ausencia de participantes en las visitas de estudio es un obstáculo importante para la finalización del ensayo clínico.
- La comprensión de los factores que influyen en la no llegada de visitas es crucial para el reclutamiento exitoso de ensayos.
Objetivo del estudio:
- Identificar las características del participante y del proceso de estudio asociadas con la no llegada a las visitas de cribado iniciales.
- Investigar los factores que influyen en la asistencia en dos ensayos controlados aleatorios (GoFresh y GoFreshRx).
Principales métodos:
- Se examinaron factores sociodemográficos y relacionados con el estudio en 2224 participantes en dos ensayos de hipertensión.
- Se utilizó la regresión logística para analizar las asociaciones con la no llegada en la visita inicial de cribado, ajustando las variables clave.
Principales resultados:
- La tasa de no llegada en la primera visita de cribado fue del 29,5%.
- La edad más avanzada se asoció con una mayor asistencia, mientras que el tamaño más grande de la familia y el tiempo más largo entre el contacto y la visita se relacionaron con la no llegada.
- El momento de la visita, la estación y el método de contacto no afectaron significativamente la asistencia.
Conclusiones:
- La edad avanzada, el tamaño más grande de la familia y los retrasos prolongados entre el contacto inicial y las visitas son factores clave asociados con la no llegada.
- Estos hallazgos sugieren objetivos potenciales para las intervenciones para mejorar la asistencia de los participantes y alcanzar los objetivos de reclutamiento.
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