Video Experimental Relacionado
Updated: Sep 10, 2025
12:18
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
7.6K
Modelos de uso de medicamentos y polifarmacia entre los ancianos en Irán: un estudio transversal utilizando datos de
Seyed Mohammad-Navid Ataei1, Ali Golestani1, Sepehr Khosravi1
1Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran (the Islamic Republic of).
BMJ open
|August 21, 2025
Resumen
La polifarmacia es muy frecuente en Irán.
Área de la Ciencia:
- Medicina para la edad avanzada
- Salud pública
- Farmacoeconomía
Sus antecedentes:
- La polifarmacia, el uso de múltiples medicamentos, plantea un desafío significativo en las poblaciones de edad avanzada, especialmente en los países de ingresos medios.
- Irán se enfrenta a una creciente preocupación con respecto al manejo de medicamentos entre su población envejecida.
Objetivo del estudio:
- Investigar la prevalencia y los patrones de polifarmacia entre las personas mayores en Irán.
- Identificar las clases de medicamentos comunes y las combinaciones de medicamentos asociadas con la polifarmacia.
- Informar las decisiones políticas y mejorar la seguridad de los medicamentos para la población de edad avanzada.
Principales métodos:
- Un estudio observacional retrospectivo basado en la población que utiliza datos de reclamos de seguro de salud a nivel nacional.
- Análisis de los datos de 1.876.527 personas de 65 años o más aseguradas por la Organización de Seguros de Salud de Irán (IHIO) entre 2014 y 2017.
- La polifarmacia se define como el uso de cinco o más medicamentos; el análisis incluyó la polifarmacia acumulativa y consecutiva, empleando regresión logística y minería de reglas de asociación.
Principales resultados:
- Se observó una alta prevalencia de polifarmacia: el 74,9% experimentó polifarmacia acumulada durante 6 meses y el 64,6% durante 1 mes.
- Las mujeres y los individuos de 75 a 79 años mostraron una mayor propensión a la polifarmacia.
- Los medicamentos comúnmente utilizados incluyen glucocorticoides sistémicos, inhibidores de la HMG-CoA reductasa e inhibidores de la agregación plaquetaria, con fuertes asociaciones encontradas para medicamentos que afectan el tracto digestivo, el sistema cardiovascular, el sistema nervioso y el sistema sanguíneo.
Conclusiones:
- La polifarmacia está muy extendida entre los ancianos en Irán, con variaciones notables basadas en género, edad, seguro y región.
- Los hallazgos subrayan la necesidad crítica de intervenciones específicas para gestionar eficazmente la polifarmacia y mejorar la seguridad de los medicamentos en este grupo demográfico.
Más Videos Relacionados
06:52Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
Published on: September 30, 2020
10.0K
11:21Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
Published on: July 27, 2018
8.3K
Videos de Conceptos Relacionados
01:02Prescription, Nonprescription and Orphan Drugs
844
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
844
01:21Factors Affecting Drug Response: Overview
2.4K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.4K
01:28Drug Therapy
97
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
97
01:15Drug Dosage Regimen: Overview
3.8K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.8K
01:12Analysis of Population Pharmacokinetic Data
382
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
382
01:15Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
124
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
124