Intervenciones psicosociales y psicofarmacológicas para el trastorno bipolar comórbido y los trastornos por consumo de sustancias: una revisión
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Broghan O'Hearn1, Nur Akpolat1, Hadi Kobaissi1
1Department of Psychiatry, Massachusetts General Hospital, (BO, NA, HK, MK, AAN, LGS, AKG), and Harvard Medical School (AAN, LGS, AKG), Boston, Massachusetts.
Psychiatric annals
|August 22, 2025
Resumen
El tratamiento del trastorno bipolar comórbido y los trastornos por consumo de sustancias es un desafío. Si bien algunas intervenciones son prometedoras para el trastorno bipolar y el consumo de sustancias, los planes personalizados y multimodales son esenciales para un manejo eficaz.
Área de la Ciencia:
- La psiquiatría
- Psicología clínica
- Medicina para la adicción
Sus antecedentes:
- El trastorno bipolar comórbido y los trastornos por consumo de sustancias (TSA) presentan desafíos clínicos complejos.
- Las estrategias de tratamiento efectivas para este diagnóstico dual son críticamente necesarias.
Objetivo del estudio:
- Revisar las intervenciones psicosociales y psicofarmacológicas para el trastorno bipolar comórbido y SUD.
- Evaluar la eficacia de estas intervenciones en ensayos controlados aleatorios.
Principales métodos:
- Revisión sistemática de ensayos aleatorizados y controlados.
- Análisis de las intervenciones dirigidas tanto a los síntomas del estado de ánimo como al consumo de sustancias.
Principales resultados:
- Varias intervenciones demostraron beneficios potenciales tanto para el trastorno bipolar como para el SUD.
- Ningún tratamiento individual superó de manera consistente al placebo en ambos dominios.
- La eficacia del tratamiento varió según las necesidades individuales del paciente.
Conclusiones:
- Los planes de tratamiento integrados y personalizados son cruciales para el manejo del trastorno bipolar comórbido y SUD.
- Se recomiendan enfoques multimodales para abordar la complejidad de este diagnóstico dual.
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