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Impacto de la pandemia de la enfermedad por coronavirus 2019 (COVID-19) en la progresión del estadio tumoral en
Alper Keskin1, Enis Mert Yorulmaz2, Kursad Donmez3
1Department of Urology, Denizli State Hospital, Denizli, Türkiye.
Frontiers in urology
|August 22, 2025
Resumen
Los retrasos en la atención durante la pandemia de COVID-19 empeoraron la etapa patológica en los cánceres de próstata y riñón. Los cánceres de vejiga y de testículo no se vieron afectados, lo que pone de relieve la necesidad de vías de tratamiento del cáncer resistentes.
Área de la Ciencia:
- Urología
- En el campo de la oncología
- Salud pública
Sus antecedentes:
- La pandemia de COVID-19 causó interrupciones significativas en los servicios de salud a nivel mundial.
- Estas interrupciones pueden haber afectado el diagnóstico y el tratamiento oportunos de varios tipos de cáncer, lo que podría conducir a la progresión de la enfermedad.
Objetivo del estudio:
- Investigar si los retrasos en la atención durante la pandemia de COVID-19 estuvieron asociados con la progresión de la etapa patológica en tumores malignos urológicos.
- Para comparar los resultados quirúrgicos entre las cohortes de la era pre-pandémica y pandémica para los cánceres de próstata, vejiga, riñón y testículo.
Principales métodos:
- Un estudio de cohorte retrospectivo comparó 368 pacientes sometidos a cirugías radicales por cáncer urológico.
- Los pacientes se dividieron en cohortes pre-pandémicas (PREP) y pandémicas (POSTP) (abril 2019 - marzo 2022).
- Se analizaron los datos clínicos, de laboratorio y patológicos utilizando las pruebas estadísticas apropiadas (p<0,05 significación).
Principales resultados:
- Los pacientes con prostatectomía POSTP mostraron un PSA más alto, una mayor participación del tumor y un aumento de la extensión extraprostática.
- Los tumores renales de la era pandémica eran más grandes con una hemoglobina preoperatoria más baja, lo que indica una enfermedad más avanzada.
- No se encontraron diferencias significativas en el estadio patológico de los cánceres de vejiga o de testículo entre las cohortes.
Conclusiones:
- Las interrupciones de la atención relacionadas con el COVID-19 se relacionaron con características patológicas adversas en los cánceres de próstata y renal.
- Los cánceres de vejiga y de testículo no presentaron una migración de estadio significativa debido a retrasos relacionados con la pandemia.
- Los hallazgos subrayan la necesidad de vías sólidas de tratamiento del cáncer para mitigar la progresión durante las crisis de salud.
Palabras clave:
El COVID-19retraso por pandemiaEstadio patológicoProgreso del tumorcánceres urológicosMás Videos Relacionados
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