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El estado actual del uso indebido de feniramina entre los pacientes con trastornos por uso de sustancias: una
Raja Babu Ramawat1, Omar Afroz1, Rizwana Quraishi2
1National Drug Dependence Treatment Centre & Department of Psychiatry, AIIMS, New Delhi, India.
The International journal of risk & safety in medicine
|August 22, 2025
Resumen
La feniramina, un antihistamínico de venta libre, muestra potencial de uso indebido y dependencia, a menudo combinado con opioides. Los médicos deben estar al tanto de sus signos, especialmente en pacientes con trastornos por consumo de sustancias.
Área de la Ciencia:
- Farmacología
- Salud pública
- Medicina Clínica
Sus antecedentes:
- Los medicamentos de venta libre (OTC) se enfrentan a una creciente preocupación por el uso indebido a nivel mundial.
- La feniramina, un antihistamínico de primera generación para alergias, es reconocida por su potencial de uso indebido y dependencia, contrariamente a su percepción inicial de seguridad.
- Las pruebas emergentes indican que la feniramina se utiliza de forma ilícita, a menudo mezclada con opioides en el consumo de drogas inyectables, pero sigue siendo poco estudiada.
Objetivo del estudio:
- Revisar la literatura existente sobre el uso indebido de la feniramina.
- Para resumir los informes de casos de uso indebido de feniramina y sus implicaciones clínicas.
Principales métodos:
- Se realizó una búsqueda exhaustiva de la literatura utilizando PubMed, Google Scholar y MedSearch.
- Se incluyeron artículos en inglés, revisados por pares e indexados por PubMed centrados en el uso indebido, el abuso, la dependencia y los trastornos relacionados con el uso de sustancias.
- Las palabras clave incluían "uso de feniramina", "uso indebido", "abuso", "dependencia", "uso nocivo", "trastorno por consumo de sustancias", "trastorno por consumo de opiáceos" y "consumidor de drogas inyectables".
Principales resultados:
- La feniramina presenta un potencial de uso indebido comparable al lorazepam y se inyecta con frecuencia, especialmente en el sur de Asia, a menudo con opioides y / o diazepam.
- Los estudios realizados en el sur de Asia indican el uso comórbido de feniramina en el 15% al 80% de los usuarios de drogas inyectables, con una subnotificación por parte de los pacientes.
- Más de ocho informes de casos detallan el uso indebido/dependencia de la feniramina, vinculado a convulsiones, psicosis y toxicidad potencialmente mortal, con fácil acceso como un factor potencial.
Conclusiones:
- El uso indebido de feniramina representa un desafío creciente para la salud pública.
- Los proveedores de atención médica deben mantener la vigilancia de los signos de abuso de feniramina, especialmente en personas con uso de sustancias y afecciones psiquiátricas que ocurren simultáneamente.
Palabras clave:
antihistamínicola dependenciausuario de drogas inyectablesEl mal usoOpioides y sus derivadosde venta libreFeniramina y sus derivadosMás Videos Relacionados
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