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Updated: Sep 10, 2025

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Evaluation of Oxidative Stress in Biological Samples Using the Thiobarbituric Acid Reactive Substances Assay
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Las puntuaciones del equilibrio oxidativo en los sobrevivientes de cáncer: un estudio transversal a nivel nacional
Jae Hyuck Lee1, In Cheol Hwang1, Hong Yup Ahn2
1Department of Family Medicine, Gil Medical Centre, Gachon University College of Medicine, Incheon, South Korea.
Resumen
Sobrevivientes de cáncer
Área de la Ciencia:
- En el campo de la oncología
- Salud pública
- La bioquímica
Sus antecedentes:
- El desequilibrio oxidativo está relacionado con resultados adversos, pero los datos sobre los sobrevivientes de cáncer son escasos.
- Los sobrevivientes de cáncer representan una población significativa con consideraciones de salud únicas.
- Comprender el equilibrio oxidativo es crucial para el manejo de la salud a largo plazo en este grupo.
Objetivo del estudio:
- Para evaluar la puntuación de equilibrio oxidativo (OBS) en los sobrevivientes de cáncer en comparación con los no sobrevivientes.
- Diferenciar entre sobrevivientes de cáncer a corto plazo (< 5 años) y a largo plazo.
- Identificar las posibles disparidades en el equilibrio oxidativo entre los subgrupos de sobrevivientes de cáncer.
Principales métodos:
- Se utilizaron datos de encuestas nacionales coreanas realizadas entre 2013 y 2020.
- Se calculó la puntuación de equilibrio oxidativo (OBS, por sus siglas en inglés) para todos los participantes del estudio.
- Categorizó a los participantes en no sobrevivientes, sobrevivientes a corto plazo y sobrevivientes a largo plazo.
Principales resultados:
- Aproximadamente el 4,6% de los participantes fueron identificados como sobrevivientes de cáncer.
- Los sobrevivientes a largo plazo constituyeron tres quintas partes de la cohorte de sobrevivientes de cáncer.
- Los hombres y mujeres sobrevivientes a corto plazo exhibieron una mayor OBS que los no sobrevivientes.
- Las mujeres sobrevivientes a largo plazo mostraron una media inversa de OBS en comparación con las no sobrevivientes.
Conclusiones:
- El equilibrio oxidativo difiere entre los grupos de sobrevivientes de cáncer y los no sobrevivientes.
- Los subgrupos específicos, como las mujeres supervivientes a largo plazo, pueden requerir intervenciones específicas en el estilo de vida.
- Los médicos deben aconsejar a los sobrevivientes de cáncer, especialmente a las mujeres, sobre los riesgos del estilo de vida que afectan el equilibrio oxidativo.
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