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Ecosistemas nacionales de investigación: protección de las poblaciones y fomento de la seguridad sanitaria en todo el
Elizabeth S Higgs1, Arshad Altaf2, Nicole Lurie3
1Division of Clinical Research, National Institute of Allergy and Infectious Diseases, Rockville, MD, USA.
The Lancet. Global health
|August 22, 2025
Resumen
La investigación clínica global está desalineada con la carga de la enfermedad, concentrando los ensayos en las naciones ricas. El fortalecimiento de los ecosistemas nacionales de investigación es esencial para abordar las necesidades mundiales de salud y prepararse para futuras crisis de salud.
Área de la Ciencia:
- Salud global
- Investigación clínica
- Fortalecimiento de los sistemas de salud
Sus antecedentes:
- Los ensayos clínicos y las capacidades de investigación se concentran en países de altos ingresos.
- Las poblaciones de los países de ingresos bajos y medios soportan la mayor carga de enfermedades, pero participan en pocos ensayos relevantes.
- Este desequilibrio crea brechas de conocimiento y deja al mundo vulnerable a las amenazas emergentes para la salud.
Objetivo del estudio:
- Proponer una visión para los ecosistemas nacionales de investigación que se alineen con las necesidades de salud pública.
- Abogar por la integración de la investigación en los sistemas de salud para la mejora oportuna de la atención sanitaria.
- Hacer hincapié en la necesidad de invertir en la capacidad mundial de investigación clínica.
Principales métodos:
- Este punto de vista sintetiza los desafíos existentes en la investigación clínica mundial.
- Propone una visión estratégica para el desarrollo de infraestructuras nacionales de investigación sólidas.
- El análisis pone de relieve la necesidad de integrar la investigación en los sistemas nacionales de salud.
Principales resultados:
- Los esfuerzos de investigación clínica mundiales actuales no abordan adecuadamente la carga mundial de las enfermedades.
- Existe una disparidad significativa en la participación en la investigación entre los países de ingresos altos y los de ingresos bajos/medios.
- Hay una necesidad crítica de sistemas de investigación que respondan a las prioridades de salud nacionales y regionales.
Conclusiones:
- Los ecosistemas nacionales de investigación fuertes son vitales para hacer frente a las necesidades de salud de la población.
- La integración de la investigación en los sistemas de salud garantiza la rápida adopción de los avances médicos.
- La inversión en la capacidad de investigación nacional e internacional es crucial para la seguridad y la preparación sanitarias mundiales.
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