Asociación entre el índice de cintura ajustado al peso de los triglicéridos y el riesgo de accidente cerebrovascular en la población general: un amplio estudio transversal de NHANES
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Ver abstracta en PubMed
Resumen
Este resumen es generado por máquina.El índice de cintura ajustado a la glucosa (TyG-WWI) está relacionado con un mayor riesgo de accidente cerebrovascular en la población general. Los niveles más altos de TyG-WWI se correlacionan con una mayor probabilidad de sufrir un derrame cerebral.
Área De La Ciencia
- Epidemiología cardiovascular
- Investigación del síndrome metabólico
- Neurología
Sus Antecedentes
- La resistencia a la insulina (IR) es un factor de riesgo conocido de accidente cerebrovascular.
- El índice de cintura ajustado a la glucosa (TyG-WWI) es un nuevo biomarcador para evaluar la IR.
- No se comprende bien la asociación entre TyG-WWI y el riesgo de accidente cerebrovascular en la población general.
Objetivo Del Estudio
- Investigar la relación entre el índice TyG-WWI y el riesgo de accidente cerebrovascular.
- Determinar si TyG-WWI puede servir como un biomarcador predictivo para el accidente cerebrovascular en la población general.
Principales Métodos
- Análisis de 22.615 participantes del programa NHANES de 1999 a 2018.
- Se utilizó regresión logística multivariada, regresión de línea cúbica restringida, análisis de subgrupos y de sensibilidad.
- Ajustado por múltiples factores de confusión potenciales.
Principales Resultados
- Cada aumento de la desviación estándar en TyG-WWI se asoció con un aumento del 15% en el riesgo de accidente cerebrovascular (OR: 1,15, IC del 95%: 1,01 a 1,32).
- Se observó una relación lineal positiva entre TyG-WWI y el riesgo de accidente cerebrovascular.
- La asociación fue más fuerte en individuos más jóvenes y en aquellos sin enfermedad coronaria.
Conclusiones
- El índice TyG-WWI demuestra una asociación lineal positiva con el riesgo de accidente cerebrovascular en la población general.
- TyG-WWI puede ser un biomarcador valioso para identificar a las personas con mayor riesgo de accidente cerebrovascular.
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