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Updated: May 7, 2026

A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces
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Morfología celular y expresión génica: seguimiento de cambios y complementariedad a través del tiempo y las líneas

Vanille Lejal1, David Rouquié2, Olivier Taboureau1

  • 1Université Paris Cité, Inserm U1133, CNRS UMR 8251, Paris, France.

Toxicology and applied pharmacology
|August 22, 2025
PubMed
Resumen

Los datos de Cell Painting y L1000 revelan cómo la exposición química altera la estructura celular y la expresión génica. Estos métodos complementarios mejoran el descubrimiento de fármacos al vincular los cambios morfológicos con los efectos moleculares.

Palabras clave:
Inhibidores de la CDKLíneas celularesPintura de las célulasEvaluación del riesgo químicoInhibidores de la HDACSe trata de:Exposición temporal

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