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Ácido tranexámico en el trauma

Whitney J Barrett1, Kevin A Kaucher2, Ross E Orpet3

  • 1Department of Emergency Medicine, University of New Mexico School of Medicine, Albuquerque, NM, National Association of EMS Physicians.

Annals of emergency medicine
|August 22, 2025
PubMed
Resumen
Este resumen es generado por máquina.

Se debate el uso del ácido tranexámico (TXA) en la atención prehospitalaria de traumas. La nueva evidencia apoya la guía actualizada para los servicios médicos de emergencia (EMS) sobre la administración de TXA intravenoso a pacientes lesionados.

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Área de la Ciencia:

  • Medicina de emergencia
  • Cuidados para traumas
  • Farmacología

Sus antecedentes:

  • El uso prehospitalario de ácido tranexámico (TXA) ha aumentado significativamente en la última década.
  • Existen pruebas contradictorias con respecto a los beneficios de la administración generalizada de TXA en pacientes con trauma.
  • La guía anterior sobre TXA prehospitalario para pacientes lesionados se emitió en 2016.

Objetivo del estudio:

  • Proporcionar recomendaciones actualizadas y basadas en la evidencia para el uso prehospitalario de TXA intravenoso en pacientes lesionados.
  • Abordar la evolución del panorama de la investigación sobre el TXA en los servicios médicos de emergencia (SME).

Principales métodos:

  • Se realizó una revisión estructurada de la literatura para sintetizar los hallazgos recientes de la investigación.
  • Se elaboraron recomendaciones basadas en la evidencia resumida en un documento de recursos adjunto.

Principales resultados:

  • La revisión identificó nuevas investigaciones que investigaban los resultados de los pacientes después de la administración de TXA antes del ingreso hospitalario.
  • Los hallazgos sirvieron de base para el desarrollo de una guía clínica actualizada.

Conclusiones:

  • La Asociación Nacional de Médicos de EMS, el Comité de Trauma del Colegio Americano de Cirujanos y el Colegio Americano de Médicos de Emergencia proporcionan recomendaciones actualizadas.
  • Estas recomendaciones guían el uso apropiado de TXA intravenoso en el entorno prehospitalario para pacientes lesionados.